王静

王静

研究员，博士生导师

E-mail：jing.wang@fjnu.edu.cn

ORCID：0000-0001-6080-7998

通讯地址：福建省福州市闽侯县福建师范大学旗山校区光电学院(350117)

主要开展基于先进纳米材料的生物医学光谱学交叉领域的研究，包括：

1. 表面增强拉曼光谱体外检测技术开发

2. 生物医学光学传感器研发

3. 床旁检测技术（point-of-care）研发

1.Jing Wang*, Quan Zhou, Kym Lowry, Christopher B. Howard and Matt Trau. Development and application of multivalent nanobody-functionalized plasmonic probes in SERS sensing platforms. Biosensors and Bioelectronics, 2025, 278, 117292. (SCI一区，IF 10.7)

2.Dechun Zhang#, Xianling Chen#, Jia Lin, Shiyan Jiang, Min Fan, Nenrong Liu*, Zufang Huang and Jing Wang*. Ultrasensitive Detection of Circulating Plasma Cells Using Surface-Enhanced Raman Spectroscopy and Machine Learning for Multiple Myeloma Monitoring. Analytical Chemistry, 2025, 97, 4101. (SCI一区，IF 6.8，封面论文)

3.Dechan Lu#, Yanping Chen#, Longfeng Ke, Zufang Huang*, Yudong Lu* and Jing Wang*. Bisulfite-free detection of DNA methylation in early-stage lung cancer with a multiplex SERS immunoassay. Chemical Engineering Journal, 2025, 503, 158491. (SCI一区，IF 13.4)

4.Zhen Zhang, Jing Wang*, Alain Wuethrich* and Matt Trau*. Conventional techniques and emerging nanotechnologies for early detection of cancer metastasis via epithelial-mesenchymal transition monitoring. National Science Review, 2024, nwae452. (SCI一区，IF 16.3)

5.Quan Zhou, Jing Wang*, Zhen Zhang, Alain Wuethrich, Richard J. Lobb* and Matt Trau*. Tracking the EMT-like phenotype switching during targeted therapy in melanoma by analyzing extracellular vesicle phenotypes. Biosensors and Bioelectronics, 2024, 244, 115819. (SCI一区，IF 10.7)

6.Min Fan#, Yan Li#, Jingbo Chen, Yuxiang Lin, Shuxia Lai, Shirun Peng, Duo Lin, Jing Wang*, Yudong Lu* and Shangyuan Feng*. Plasmonic internal standard-decorated nitrocellulose membranes for duplex detection of circulating tumor biomarkers. Sensors and Actuators B: Chemical, 2023, 395, 134508(SCI一区，IF 8)

7.Weiming Lin#, Liwen Yuan, Zehang Gao, Gaozhe Cai, Cheng Liang, Min Fan, Xianjie Xiu, Zufang Huang*, Shilun Feng*, Jing Wang*. An integrated sample-to-answer SERS platform for multiplex phenotyping of extracellular vesicles. Sensors and Actuators B: Chemical, 2023, 394, 134355. (SCI一区，IF 8)

8.Liwen Yuan#, Yanpin Chen#, Longfeng Ke, Quan Zhou, Jiayou Chen, Min Fan, Alain Wuethrich*, Matt Trau* and Jing Wang*. Plasma extracellular vesicle phenotyping for the differentiation of early-stage lung cancer and benign lung disease. Nanoscale Horizons, 2023, 8, 746. (SCI二区，IF 9.7，封面论文)

9.Dechan Lu#, Yanping Chen#, Longfeng Ke, Weilin Wu, Liwen Yuan, Shangyuan Feng, Zufang Huang*, Yudong Lu* and Jing Wang*. Machine learning-assisted global DNA methylation fingerprint analysis for differentiating early-stage lung cancer from benign lung diseases. Biosensors and Bioelectronics, 2023, 115235. (SCI一区，IF 10.7)

10.Jing Wang, Kevin M. Koo* and Matt Trau*. Tetraplex Immunophenotyping of Cell Surface Proteomes via Synthesized Plasmonic Nanotags and Portable Raman Spectroscopy. Analytical Chemistry, 2022, 94, 14906-14916. (SCI一区，IF 7.4)

11.Junrong Li#, Alain Wuethrich#, Zhen Zhang, Jing Wang*, Lynlee L. Lin, Andreas Behren*, Yuling Wang* and Matt Trau*. SERS Multiplex Profiling of Melanoma Circulating Tumor Cells for Predicting the Response to Immune Checkpoint Blockade Therapy. Analytical Chemistry, 2022, 94, 14573-14582. (SCI一区，IF 7.4)

12.Weiming Lin, Shuxia Lai, Dechan Lu, Qun Zhang, Xueliang Lin, Juqiang Lin, Jing Wang* and Zufang Huang*. An acousto-assisted liquid-marble-based microreactor for quantitative SERS detection of alkaline phosphatase. Sensors and Actuators B: Chemical, 2022, 356. (SCI一区，IF 8.4)

13.Cairou Chen#, Jing Wang#, Dechan Lu, Ruiyun You*, Qiutian She, Jingbo Chen, Shangyuan Feng* and Yudong Lu*. Early detection of lung cancer via biointerference-free, target microRNA-triggered core-satellite nanocomposites. Nanoscale, 2022, 14, 8103-8111. (SCI一区，IF 6.7)

14.Zhen Zhang#, Alain Wuethrich#, Jing Wang*, Darren Korbie, Lynlee. L. Lin* and Matt Trau*. Dynamic Monitoring of EMT in CTCs as an Indicator of Cancer Metastasis. Analytical Chemistry, 2021, 93 (50), 16787-16795. (SCI一区，IF 6.4)

15.Jing Wang†, Yung-Ching Kao†, Quan Zhou, Alain Wuethrich*, Mitchell S. Stark, Helmut Schaider, H. Peter Soyer, Lynlee L. Lin* and Matt Trau*. An Integrated Microfluidic-SERS Platform Enables Sensitive Phenotyping of Serum Extracellular Vesicles in Early Stage Melanomas. Advanced Functional Materials, 2021, 2010296. (SCI一区，IF 18.8)

16.Jing Wang, Alain Wuethrich*, Richard J. Lobb, Fiach Antaw, Abu Ali Ibn Sina, Rebecca E. Lane, Quan Zhou, Chloe Zieschank, Caroline Bell, Vanessa F. Bonazzi, Lauren G. Aoude, Sarah Everitt, Belinda Yeo, Andrew P. Barbour, Andreas Möller and Matt Trau*. Characterizing the Heterogeneity of Small Extracellular Vesicle Populations in Multiple Cancer Types via an Ultrasensitive Chip. ACS Sensors, 2021, 6, 3182–3194. (SCI一区，IF 7.7，封面论文)

17.Jing Wang†, Alain Wuethrich†, Abu Ali Ibn Sina, Rebecca E. Lane, Lynlee L. Lin, Yuling Wang*, Jonathan Cebon, Andreas Behren and Matt Trau*. Tracking Extracellular Vesicle Phenotypic Changes Enables Treatment Monitoring in Melanoma. Science Advances, 2020, 6, eaax3223. (Science子刊，IF 14.1)

18.Zhen Zhang†, Jing Wang†, Karthik Balaji Shanmugasundaram, Belinda Yeo, Andreas Möller, Alain Wuethrich*, Lynlee L. Lin* and Matt Trau*. Tracking drug-induced epithelial-mesenchymal transition in breast cancer by a microfluidic surface-enhanced Raman spectroscopy immunoassay. Small, 2020, 1905614. (SCI一区，IF 13.3)

19.Jing Wang, Kevin M. Koo*, Yuling Wang* and Matt Trau*. Engineering State-of-the-Art Plasmonic Nanomaterials for SERS-Based Clinical Liquid Biopsy Applications. Advanced Science, 2019, 6, 1900730. (SCI一区，IF 15.8)

20.Jing Wang†, Will Anderson†, Junrong Li, Lynlee L. Lin, Yuling Wang* and Matt Trau*. High-resolution Study of in situ Surface-enhanced Raman Scattering Nanotag Behavior in Biological Systems. Journal of Colloid and Interface Science, 2019, 537, 536-546.  (SCI二区，IF 7.5)

21.Jing Wang†, Kevin M. Koo†, Yuling Wang* and Matt Trau*. Mix-to-Go Silver Colloidal Strategy for Prostate Cancer Molecular Profiling and Risk Prediction. Analytical chemistry, 2018, 90 (21), 12698-12705. (SCI一区，IF 6.4)

22.Kevin M Koo†, Jing Wang†, Renée S Richards, Aine Farrell, John W Yaxley, Hema Samaratunga, Patrick E Teloken, Matthew J Roberts, Geoffrey D Coughlin, Martin F Lavin, Paul N Mainwaring, Yuling Wang, Robert A Gardiner and Matt Trau*. Design and Clinical Verification of Surface-Enhanced Raman Spectroscopy Diagnostic Technology for Individual Cancer Risk Prediction. ACS Nano, 2018, 12 (8), 8362-8371. (SCI一区，IF 13.9)

23.Junrong Li†, Jing Wang†, Yadveer S Grewal, Christopher B Howard, Lyndon J Raftery, Stephen Mahler, Yuling Wang* and Matt Trau*. Multiplexed SERS Detection of Soluble Cancer Protein Biomarkers with Gold-Silver Alloy Nanoboxes and Nanoyeast Single-Chain Variable Fragments. Analytical Chemistry, 2018, 90 (17), 10377-10384. (SCI一区，IF 6.4)

24.Simon Chang-Hao Tsao†, Jing Wang†, Yuling Wang*, Andreas Behren, Jonathan Cebon and Matt Trau*. Characterising the Phenotypic Evolution of Circulating Tumour Cells during Treatment. Nature Communications, 2018, 9 (1), 1482. (Nature子刊，IF 11.9)

25.Jing Wang†, Kevin M Koo†, Eugene JH Wee*, Yuling Wang* and Matt Trau*. A Nanoplasmonic Label-Free Surface-Enhanced Raman Scattering Strategy for Non-Invasive Cancer Genetic Subtyping in Patient Samples. Nanoscale, 2017, 9 (10), 3496-3503. (SCI一区，IF 7.2)

26.Khondakar Kamil Reza†, Jing Wang†, Ramanathan Vaidyanathan, Shuvashis Dey, Yuling Wang* and Matt Trau*. Electrohydrodynamic-Induced Sers Immunoassay for Extensive Multiplexed Biomarker Sensing. Small, 2017, 13 (9), 1602902. (SCI一区，IF 9.6)

1.国家自然科学基金面上项目，12074069，主持，63万，已结题

2.福建省“雏鹰计划”青年拔尖人才项目，主持，200万，在研

3.福建省“闽江学者”特聘教授人才项目，主持，200万，已结题

4.福建省优秀青年科学基金项目，2024J09030，主持，20万，在研

5.福建省联合创新课题攀登项目，2021Y9228，合作单位负责人，45万，在研

6.福建省引导性项目，2023Y0058，合作单位负责人，15万，在研

7.Mark Hughes Foundation Brain Cancer Innovation Project Grants，参与，AU$200,000，已结题

8.HCRA Biomarkers and Targeted Therapies Flagship Program，参与，AU$11,000，已结题

1.2015年澳大利亚国际研究生奖学金

2.2018年中国国家优秀自费留学生奖学金

3.作为第一指导教师指导学生获得中国国际大学生创新大赛银奖、“挑战杯”铜奖、全国大学生光电设计竞赛一等奖。