张先增教授、博/硕导,光电与信息工程学院院长/党委副书记、医学光电信息技术福建省2011协同创新中心主任、光电信息工程专业硕士点负责人、光电信息科学与工程国家级一流本科专业负责人、福建省医学会激光医学专科分会主任委员、福州市光电行业协会名誉会长、福建省集成电路产教融合创新发展联盟副理事长,福建省人工智能科教协会副会长、全国大学生光电设计竞赛东南区竞赛委员会秘书长,教育部光电信息专业教学指导分委员会协作委员。2014-2016 美国科罗拉多大学访问教授。
² 研究方向:
n 硬组织光子学(激光消融技术)
n 光电传感技术与生命体征检测
n 生医光电材料与医疗器械
² 科研项目情况:
1. 科学级高灵敏度成像系统高信噪比及自动曝光算法设计,公司委托项目,2022. 04-2023. 12,主持
2. “抗菌-促骨结合”双功能种植体压电声控涂层的构建和机制研究,福建省科技创新联合资金项目,2022-2025,合作主持
3. 生物硬组织激光消融水介导增强效应作用机理的研究,国家自然科学基金面上项目(61575042),2016.01-2019.12,主持
4. 伴水喷雾介导增强生物硬组织激光消融效应的研究,福建省自然科学基金,2017. 04-2020. 04,主持
5. 鼻咽癌转移机制与LMP1蛋白关联性的可视化光学表达,国家自然科学基金面上项目(61475036),2015.01-2018.12,合作主持
6. 脉冲激光生物硬组织水介导消融效应的机制研究. 教育厅重点项目,2011.05-2014.05,主持
7. 多光子显微成像结合拉曼光谱技术用于结直肠癌诊断和评估. 国家自然科学基金青年项目(61575042),2014.01-2016.12,第二成员
² 期刊论文 ( Selected)
1. Yanli Huang, Boyan Lv, Chunlin Zhao, Jie Yin, Yabin Wang, Yang Wang, Xinmiao Fu, Tianmin Wu, Jiagang Wu, Xianzeng Zhang*. High‐Efficiency Reactive Oxygen Species Generation by Multiphase and TiO6 Distortion‐Mediated Superior Piezocatalysis in Perovskite Ferroelectrics[J]. Advanced Functional Materials, 2023: 2210726
2. Yanjin Lu, Yuan Zhou, Xiongwei Liang, Xianzeng Zhang*. Chengke Zhang*., Min Zhu, Kanglai Tang*. Jinxin Lin. Early bone ingrowth of Cu-bearing CoCr scaffolds produced by selective laser melting: An in vitro and in vivo study, Materials & Design, 2023,228, 111822
3. Yanli Huang, Chunlin Zhao, Bo Wu, Xianzeng Zhang*. Grain size effects and structure origin in high-performance BaTiO3-based piezoceramics with large grains, Journal of the European Ceramic Society, 2022, 42(6): 2764-2771
4. 薛建伟,吴灵锦,石晓卫,黄靖,梁航,张先增. 9.3 μm脉冲CO2激光辐照牙硬组织的消融特性研究[J].中国激光, 2022, 第49卷(15): 55-60
5. Ying Wang, Zhihao Chen, Weijuan Chen, Xianzeng Zhang*. Refractive index and temperature sensor based on fiber ring laser with tapered seven core fiber structure in 2 μm band, Optical Fiber Technology, 2021, 61: 0-102388
6. 吕茗萱,石晓卫,薛建伟,吴灵锦,张先增*.激光诱导液体微射流效应及其在医学领域的应用[J].激光与光电子学进展,2021,第58卷(11): 51-58
7. 石晓卫,苑慧,吕茗萱,蔡佳惠,张先增*.虚拟现实技术在医学领域的研究现状与进展[J].激光与光电子学进展, 2020, 第57卷(1): 66-75
8. Xianzeng Zhang, Nenrong Liu, Mak PU, Pun SH, Vai MI, Masihzadeh O, Kahook MY, Lei TC, Ammar DA. Three-Dimensional Segmentation and Quantitative Measurement of the Aqueous Outflow System of Intact Mouse Eyes Based on Spectral Two-Photon Microscopy Techniques. Invest Ophthalmol Vis Sci. 2016, 57(7):3159-67.
9. Xianzeng Zhang, Chen Chuanguo, Chen Faner, Zhan Zhenlin, Xie Shusen, Ye Qing. In vitro investigation on Ho: YAG laser-assisted bone ablation underwater, Lasers in Medical Science, 2016,31(5): 891-898
10. Zhang Xianzeng, Zhenlin Zhan, Haibin Zhao, et al.. Influence of water-layer thickness on hard tissue ablation with pulse CO2 laser.Journal of Biomedical Optics,2012, 17(3):038003
11. 李旭伟,陈传国,张先增*,詹振林,谢树森. 聚焦辐照条件对脉冲CO2激光诱导液体气穴通道效应的影响. 光学学报, 2015, 35(2): 0217001
12. Zhang Xianzeng, Gen Yan, Ye Qin, et al.. Volumetric label-free imaging and 3D reconstruction of mammalian cochlea based on two-photon excitation fluorescence microscopy. Laser physics. 2013, 23(11): 115601
13. Liu Nenrong, Xianzeng Zhang*, Qiu Yishen, et al.. Nonlinear optical imaging characteristics in rat tail tendon. Laser Physics Letters. 2013. 23(11): 115601
14. Zhenlin Zhan, Xianzeng Zhang*, Wenqing Guo, et al. Assessment of composition changes in demineralization and remineralization of human dentin using Raman spectroscopy. Photonics & Lasers in Medicine, 2013, 2(1):45-50.
15. Zhenlin Zhan, Xianzeng Zhang*, Wenqing Guo, et al. Determining ablation threshold of dental hard tissues irradiated with Er:YAG and Er,Cr:YSGG laser. Chinese Optics Letters. 2013, 11(5)
16. 张先增,郭健,詹振林,谢树森. 脉冲CO2激光伴水喷雾的骨组织消融. 光学学报. 2010, 30(7): 2069-2073
17. Zhang Xianzeng, Xie Shusen, Zhan Zhenlin, et al.. Evaluation of Er, Cr:YSGG laser for hard tissue ablation. Frontier of Optoelectronics in China. 2010, 3(2) :163-168
18. 赵海滨,张先增,詹振林,谢树森. 组织表面附着水膜层对脉冲CO2激光骨硬组织消融的影响. 中国激光, 2011, 38(1): 0104002。
19. 詹振林,张先增, 郭文庆, 刘海山, 谢树森. 牙硬组织消融光学研究进展. 激光与光电子学进展, 2012, 49(10): 100005。
20. Zhang Xianzeng, Xie Shusen, Ye Qing, et al.. Influence of scanning velocity on bovine shank bone ablation with pulsed CO2 laser. Chinese Optics Letters, 2009, 7(2): 138-141
21. 张先增,王晓燕,詹振林,等. 脉冲CO2和Er:YAG激光颅骨组织消融的比较研究.中国激光, 2009, 36(10):2577-2581
22. Zhang Xianzeng, Wang Xiaoyan, Zhan Zhenlin, et al.. Fenestration operation in middle ear bone with pulse infrared lasers: an in-vivo study. Chinese Optics Letters, 2009, 7(9):830-833
23. 张先增,谢树森,詹振林,叶青. 脉冲激光生物硬组织消融的研究进展. 激光与光电子学进展, 2009, 46(12): 72-79
² 授权发明专利:
1. 张先增,张晓奇. 一种基于视频提取脉搏波的血压检测方法及终端. CN1188092B, 2022-08-19, 32.
2. 张先增,卢智全,吴剑峰,连渊坡,一种非接触式复杂表面锥体体积测量系统及方法,2014.12.10,中国,CN201410446494.6
3. 张先增,詹振林,刘海山,谢树森,一种水膜层厚度的精确控制调节装置,2013.06.05,中国,CN201110137705.4
4. 张先增,詹振林,刘海山,赵海滨,谢树森,容器内液面高度精确调节控制装置,2011.12.14,中国,CN201120170854.6