时间：2017年12月19日（周二）下午 3:00
地点：光电与信息工程学院仓山校区四层学术报告厅
主讲： Professor Tim C. Lei, 教授
主办：福建师范大学光电与信息工程学院、医学光电科学与技术教育部重点实验室、福建省光子技术重点实验室、福建省光电传感应用工程技术研究中心
专家简介：
Dr. Lei is an associate professor in the Department of Electrical Engineering at the Downtown Campus of the University of Colorado Denver. He also holds adjunct faculty positions in the Departments of Bioengineering, Physiology & Biophysics and Medicine. He is an expert in advanced fluorescence microscopy techniques, multiphoton microscopy and spectroscopic techniques in biological systems. He is currently working on using these techniques to understand phosphate imbalance in chronic kidney disease, progression and treatment of glaucoma in the eye, developing optical and electronic devices to understand Parkinson's disease with optogenetic protein technology, and study the nonlinear optical response of next generation photodynamic therapy drugs. He has developed several courses in optics and biophotonics in the graduate level. He also teaches several undergraduate level courses in electrical engineering including circuit design and microelectronics.
报告简介：
The human brain consists of roughly 80 billion neurons by which this massive parallel computer is formed to process almost all neuronal signals in the human body. All physical behaviors and emotional responses of a human are direct results of action potential firing and signal processing by these neuronal networks. However, our understanding of how many of these neuronal circuits function is still fairly basic. Because of this lack of knowledge, many neurophysiological disorders, such as Parkinson’s disease, Schizophrenia and depression, are therefore untreatable under most physiological conditions. This situation started to change recently due to the developments of several new techniques in neuroscience studies. These advancements include deep brain stimulation in treating severe Parkinson’s disease, as well as using optogenetic proteins to selectively stimulate or to inhibit firings of action potentials through optical illuminations. Despite the successes, the control scheme of these treatments or experiments are often open-looped. Since the open-looped control scheme does not monitor neuronal signals in real-time, the neuronal manipulation are either not optimized or not able to adjust the stimulation level according to the brain condition. In this talk, I will discuss several technical developments that we are working on with the goal to allow closed-loop neuronal control in real-time.
